ABOUT THE BOOK

Title: International Conference on Sustainable Biotechnology for Viksit Bharat

Editors: Dr. Santosh Kumar Mishra; Dr. Ashwini Kumar; Dr. Mohit Kumar; Prof. Sushant Singh
Published by: SAAR Publications [Reg.]
Publisher’s Address: A-09, Sita Ram Colony, Balkeshwar, Agra, Uttar Pradesh – 282004
Language: English
Pages: 470
Edition: July 2025
ISBN: 978-81-989048-3-6
DOI: 10.21276/saar/9788198904836
Citation: Mishra, S. K., Kumar, A., Kumar, M., & Singh, S. (2025). International Conference on Sustainable Biotechnology for Viksit Bharat. https://doi.org/10.21276/saar/9788198904836

Emerging Trends and Innovations in Life Sciences: A Book on Research-Based Learning Projects of Undergraduate and Postgraduate Studies

The 21st century has witnessed remarkable advancements in Life Sciences, opening new frontiers in health, environment, agriculture, and biotechnology. Central to this progress is the transformation of education systems that empower young minds to actively participate in solving real-world scientific challenges. The book, Emerging Trends and Innovations in Life Sciences is a significant stride toward bridging the gap between academic learning and practical application. This compilation showcases the Research-Based Learning (RBL) projects undertaken by undergraduate and postgraduate students of the Department of Life Sciences, Sharda School of Bioscience and Technology, Sharda University, Greater Noida, U.P., India. RBL has proven to be a transformative pedagogical approach that fosters critical thinking, curiosity, and hands-on experimentation—moving beyond routine learning to cultivate inquiry-driven exploration. In disciplines like life sciences, where observation, experimentation, and evidence-based reasoning are fundamental, such an approach is not only valuable but imperative. This book brings together a wide range of interdisciplinary research projects in areas including biotechnology, molecular biology, bioinformatics, microbiology, nanotechnology, environmental science, food science, and healthcare innovation. Each chapter reflects both scientific rigor and the potential for impactful contributions to sustainability, public health, and technological development. What sets this volume apart is its focus on the research journey itself—the process of ideation, experimentation, and problem-solving guided by dedicated faculty mentors. Their support has nurtured a culture of mentorship and collaborative learning, enriching students both academically and personally. This book serves as an inspiration for students to embrace research, a guide for educators to embed inquiry in curricula, and a glimpse for industry and academia into the creativity of young scientists

Dr. Santosh Kumar Mishra is working as an Associate Professor & HOD in the Department of Life Sciences. Dr. Mishra has completed his M.Tech.. in Biotechnology from the Institute of Engineering & Technology, Lucknow, U.P., and his Ph.D. research work from the Indian Institute of Technology, Roorkee. He has received his Ph.D. Degree from Dr. A.P.J. Abdul Kalam Technical University, Lucknow. He has more than 20 years of teaching, research, and academic administration experience. Before joining Sharda University, he was associated with IMS Engineering College, Ghaziabad. He has supervised 8 M. Tech students’ dissertation work in different areas of biological sciences. He has published 27 research publications in international peer-reviewed journals, 14 book chapters in edited books, and has also presented his work at various national and international conferences. Dr. Mishra is a dedicated and passionate teacher committed to research and innovation. He has rich experience in the NBA and NAAC accreditation processes and served as an IQAC member. Dr. Mishra has served as an Editorial Board Member & reviewer in prestigious international journals. He has also worked as Editor in Chief of a Bi-annual student magazine. Member Board of Studies, Dr. A.P.J. Abdul Kalam Technical University, Lucknow. He is a Life member of the Biotech Research Society, India (BRSI). He has also received the Excellence in Teaching award from the Society for Bioinformatics and Biological Sciences (SBBS) in recognition of outstanding scientific contribution in the field of Biotechnology for the year 2017.

Dr Ashwini Kumar is presently working as an Assistant Professor in the Department of Life Sciences, Sharda School of Bioscience and Technology, Sharda University, Greater Noida, Uttar Pradesh. Previously, he has served as an Assistant Professor in the Biotechnology and Bioinformatics Area at NIIT University, Neemrana (Rajasthan), Department of Biotechnology at IMS Engineering College, Ghaziabad, and as a Lecturer in the Department of Biotechnology, National Institute of Technology, Raipur, Chhattisgarh. The central component of Dr Kumar’s research has been biomaterial science, specifically in the field of novel drug delivery systems. The target applications of his research are formulating non-invasive and minimally invasive drug delivery approaches for better results, both in terms of pharmaceutics and patient compliance. His interest also lies in the field of tissue engineering, diabetes, and drug discovery. He has authored 24 journal articles in national and international journals, 13 book chapters, and a book. He also holds a patent on his work from PhD. He has been invited as a speaker and jury member on various national scientific platforms. He is an Editor at Nature Scientific Reports, an Associate Editor for Frontiers in System Biology, Associate Editor for Frontiers in Endocrinology, Review Editor for Frontiers in Oncology (Section – Gastrointestinal Oncology), a guest editor of Frontiers in Medical Technology, and a reviewer of Frontiers in Pharmacology, Frontiers in Oncology, Food Hydrocolloids for Health (Elsevier), Cancer Reports (Wiley), Materials and Design (Elsevier), Redox Report (Taylor & Francis), and Diabetic Medicine (Wiley). He is a life member of the Asian Polymer Association

Dr. Mohit is an active researcher and academician whose work focuses on Bio-nanotechnology and Biomaterials. He has a PhD in Biotechnology from the National Institute of Technology, Raipur, Chhattisgarh, India. He received an Institute scholarship while pursuing his doctorate. Several research articles have been published in renowned journals of Elsevier, Springer, and others, like Journal of Water Process Engineering, Journal of Environmental Chemical Engineering, etc. He has published around 08 research articles in reputable journals and has presented their findings at various International and national conferences and seminars.

Prof. (Dr.) Sushant Singh is currently working as a Professor in the Department of Life Sciences at the Sharda School of Bio-Science & Technology, Sharda University. He earned his Ph.D. in Biotechnology from IIT Guwahati in July 2014 and has extensive postdoctoral research experience at leading institutions, including the University of Central Florida, Ohio State University, and the SBP Medical Discovery Institute in the USA. Dr. Singh’s impressive contributions to research include 14 patents (1 International and 13 National) and over 50 research articles published in peer-reviewed international journals. He has presented his work at more than 50 International and National conferences, frequently as a keynote speaker, and has received numerous accolades for his contributions. As an active reviewer for esteemed journals in Biotechnology, Nanotechnology, and Life Sciences, Dr. Singh is recognized for his critical insights and expertise. His research excellence is further highlighted by his success in securing funding as a Principal Investigator for SERB(SRG), MSME Idea Grant for Prototype Development, and Sharda University Research Seed Fund, a research project. Beyond his research achievements, Dr. Singh is deeply committed to fostering innovation and entrepreneurship. As a Member of the Innovation Ambassador at the Ministry of Education’s Innovation Cell (MIC), Government of India, he actively promotes entrepreneurial initiatives and innovative thinking in academia and beyond.

TABLE OF CONTENTS

1 Cellular Engineering as Future Medicine
Amulya K Panda 		1
2 Tissue-Mimetic Microfluidic Models for Biomedical Research and Drug Discovery
Abhijit Majumder 		4
3 Biobased polymers and materials for sustainable bioeconomy
Vijai Kumar Gupta 		5
4 Bioinspired Engineering: Learning Science from Nature
Pradeep K. Srivastava 		6
5 Structure-Based drug Discovery for mitigation of Pseudomonas aeruginosa Biofilms
Deepti Jain 		8
6 Challenges in Exploiting Streptomyces in Biomanufacturing
Deepanshi Rajput, Kashyap Kumar Dubey 		9
7 Microbial Cell Factory Engineering for Biotechnological Applications
Vijai Singh 		10
8 Agro-Resource Recovery from Organic Waste: A Cascading Biorefinery Approach
Shon George Shiju, Krishnakumar Chullipalliyalil, Patrick Quille, Niall O’Leary, Brijesh K Tiwari and Gaurav Rajauria 		11
9 Insights in the Chitin Metabolism of Pathogenic Oomycetes as Promising Target for Fungicide Development and Biocontrol
Vaibhav Srivastava 		13
10 Mechanistic insights into Parkinson’s Disease: New Hopes for the Old Disease
Amal Chandra Mondal 		14
11 Hunting for Proteoform Biomarkers: Needles in a Stack of Needles?
Amit Yadav 		16
12 High-cell-Density Strategies to Maximise Bacterial Production of Biopolymers through Valorisation of Waste Streams
Federico Cerrone, Reeta Davis, Tanja Narancic, Kevin E. O’Connor 		17
13 Developing Tissue Engineered Strategies for Traumatic Spine Injuries
Akshay Srivastava 		19
14 Diagnostics: Advancing Precision and Efficiency
Meghna Singh 		21
15 Sustainable Remediation of Oily Sludge Using Microalgal-Based Phycoremediation: A Green Pathway to Industrial Waste Management
Piyush Parkhey 		22
16 Sustainable Hydrogel for Wound Healing: Cellulose-Based Innovation from Sugarcane Bagasse
Iram Jahan, Sushant Singh 		27
17 Piperine-Loaded PLGA Nanoparticles as Anti-Cancer Drug Carriers
Jaspreet Kaur, Abhijeet Joshi 		28
18 Electrochemical Biosensors for Food Safety and Quality Monitoring: Emerging Smart Technologies for Contaminant Detection
Nikita Rawal, Ranjana Pande 		29
19 Enhanced Energy Enhanced Energy Recovery from Fruit Waste by Integrating Dark Fermentation with a Bioelectrochemical System
Soumyajit Chandra, Soumya Pandit 		30
20 Ultrasound-assisted Extraction of Fructo-Oligosaccharides from lantain Peel: Optimization using Genetic Algorithm, Response Surface Methodology and Prebiotic Activity Evaluation
Pallavi Singh, Aditi Kundu, Minakshi Grover, Supradip Saha 		31
21 Nano-enabled Solutions for Sustainable Agriculture and Food Security
Rakhi, Ila Ruchiea and Roma Pandey 		33
22 Development of QCF@PLA Nanomedicine for Visceral Leishmaniasis Treatment
Shallu Sharma, Piyush Kumar Gupta, Shikha Singh 		34
23 Plant Mediated Synthesis of Nanomaterial for Energy Application
Tripti Singh 		35
24 Targeting cIAP1 in the Management of Liver Cirrhosis
Priyanka Rajput 		36
25 Effect of Lanthanum on Growth, Macromolecules and Stress Physiology of Chlorella sp.
Aryan Singh 		37
26 Temple 2 Fuel: A Zero Waste Green Hydrogen Production.
Poulami Sarkar, Piyali Das, Srijoni Banerjee 		38
27 Comparative In Silico Characterization of Adhesins and Cell Surface Proteins in Human Enteric Pathogens Implicated in Plant Colonization
Mittali Tyagi, Prabir K Paul, Rashmi Rameshwari 		40
28 Valorization of Agro-Industrial Waste for Economical Biosurfactant Production by Pseudomonas aeruginosa LS8
Pallavi Gupta, Prachi Gaur, Rachana Singh 		41
29 Utilization of Algae for Bioremediation of Wastewater and Biomass Production
Shreya Bhatt, Shashank Maurya, Rabab Anjum 		43
30 Assessment of Antibiofilm Potencies of Oleic Acid and Indole-3-butyric acid against Pseudomonas aeruginosa
Humma Niaz Malik, Prasun Kumar, Subhasree Ray 		44
31 Harnessing Ficus religiosa Phytochemicals to Disrupt the MDM2–CDK4 Pathway: A Computational Approach Against Dedifferentiated Liposarcoma
Amisha Singh, Gautam Ashish, Raja and Pallavi Dan 		45
32 Bacterial Cellulose and its Applications
Aryan Vij 		46
33 A Review on the Identification of Potential Compounds Present in Terminalia arjuna for the Treatment of Cardiovascular Disease
Shruti Prakash, Vineet Kumar, Rachana Swarnakar, Pallavi Dan 		47
34 Effect of Resection on Survival in Glioblastoma Multiforme
Jaskirat Kaur Sohal, Bibhawari Singh, Milind Dayal, Dheeraj Sharma, Parul Sharma 		49
35 Rethinking the Brain Death Paradigm: A Comprehensive Examination of Brain-Dead Reverse Hypothesis and Its Implications for Neuroscience, Ethics, and Transplant Medicine
Reetu Yadav, Tripti, Ankur Kumar, Pragati Singh 		50
36 Nanoparticles in Medical Diagnostics: A Review of Nanosensors, Imaging Agents, and Theragnostic Platforms
Ankur Kumar, Tripti, Pragati Singh, Reetu Yadav 		52
37 Isolation and Characterization of Silicase Producing Bacteria for Sustainable Production of Silicon based Biofertilizers
Oinam Bidyarani Devi, Santosh Kumar Mishra 		54
38 Parametric optimization of cellulase enzyme production using isolated novel strain of Bacillus cereus
Atul K. Verma, Santosh Kumar Mishra, Mohit Kumar 		55
39 Development of Biodegradable Sanitary Napkins Using PHB and Cellulose Extracted from Microbial and Agricultural Sources for Sustainable Menstrual Waste Management
Faiza Nasir, Ananya Bhaskar, Ekta, Tanisha Sharma, Rabab Anjum 		56
40 Sustainable Energy Resources best way for developing India: A Crucial Approach
Praveen Chandra Jha, Piyus Kumar Patha 		57
41 In Silico-guided Nanoformulation of Naringenin-loaded PLGA Nanoparticles for Reversing p-glycoprotein-mediated Multidrug Resistance in Temporal Lobe Epilepsy
Adhaar Kohli, Shalini Sharma, Vibha Rani, Shweta Dang 		58
42 Harnessing Plant Cell Culture for Mental Health: A Review of Plant Metabolites Production and Therapeutic Potential
Akarsh Sharma, Aditi Bansal, Rabab Anjum 		60
43 Beyond the Shot: Understanding Awareness, Perceptions, and Outcomes of COVID-19 Vaccinations.
Anika Sharma, G. Subha, Abhishek Jamniya, Ritik Choudhary, Parul Sharma 		61
44 Plastic-Degrading Microbes: Synthetic Biology Tools to Tackle Ocean Waste
Jahanvi Sharma 		62
45 Valorization of jackfruit (Artocarpus heterophyllus) waste for its potential application in bioethanol
Shivani Kohli, Sujata Pandit Sharma 		64
46 Emerging Lung Cancer Models and AI-Based Screening Approaches: A Path Toward Precision Medicine.
Tanya Agarwal, Madhav Saran and Pankaj Verma 		65
47 Members of the Enterobacterales Order’s Contribution to Enhancing Soil Aggregation and Seed Vigour in the Acidic Soil of West Bengal’s sub-Himalayan Terai Region Caused by Heavy Rainfall
Srija Pal, K. Karmakar 		66
48 Synergistic Pretreatment Approach Using Deep Eutectic Solvent and Microwave Irradiation for Bioconversion of Lantana Camara to Bioethanol
Diksha Sawhneya, Ila Ruchieb, Prabhat Kumara, Roma Pandey 		69
49 Assessment of Vitamin D2 Concentration in Ultraviolet-irradiated Dried Cordyceps militaris Powder
Dolly Chauhan 		71
50 Evaluation of Antioxidant Activity of Ethanolic Extract of Sunflower (Helianthus annuus) Using the DPPH Method and Quantification of Total Phenolic and Flavonoid Contents Payal Dhankani, Shivi Srivastava, Sangram Singh,
Manikant Tripathi, Pankaj Singh 		72
51 Utilization of Carboxymethyl Cellulose from Corn Cobs for Synthesis of Biodegradable Food Grade Polymeric Film
Nikita Singh, Sujata Pandit Sharma 		73
52 AUTOSHECH – Smart Solar-Powered Drip Irrigation System with Integrated Fertigation and IoT Control: A Sustainable Leap for Smallholder Farmers
Sadhika Bose 		75
53 Morphological and Biochemical Diversity of Dragon Fruits in India and Their Pharmacological Applications
Tripti Shukla, Pankaj Singh, Neelam Pathak, Manikant Tripathi 		77
54 Evaluating the Efficacy of Alkaline-dehydrated Urine-based Biofertilizer on Plant Growth and Soil Properties
Shivram Karthik, Maitry Chauhan, Muskan Gupta, Garima Mittal, Alok Kumar Singh 		79
55 Integrating Computational Driven Gene Essentiality Prediction, CRISPR dCas9 Based Drug Target Validation and Drug Repurposing Approach to Combat MDR Klebsiella Pneumoniae Causing UTIs.
Khushal Khambhati, Vijai Singh 		80
56 Biosurfactant-Stabilized Silver Nanoparticles: A Synergistic Nanotool Against Biofilm-Forming Pathogens
Babita Thakur, Sukhminderjit Kaur 		82
57 The Sustainable Microalgae Feedstock Development for Biodiesel Production
Megha Arora, Kakoli Dutt 		83
58 Biodegradable Nano-Carriers for Targeted Drug Delivery in Chronic Diseases
Khooshi Tandel 		84
59 Development and Evaluation of PLGA-Encapsulated Nanodrugs from Repurposed FDA Compounds for Targeted Therapy Against Visceral Leishmaniasis
Lalit Nharwal, Mirza Adil Beg, Nazeer Hasan, Farhan J. Ahmad, Angamuthu Selvapandiyan, Garima Chouhan 		86
60 Isolation and Molecular Characterization of a Chemotrophic Bacterium with Potential Dye-degrading Capabilities
Aditi Singh, Nupur 		87
61 Lichens as a Source of Drug Leads: An ADMET-Based Investigation of Natural Compounds
Sonali, Devvret Verma, Sugam Gupta 		88
62 Plant Hormonal Networks in Detoxification and Sequestration of Heavy Metals
Aditi Bansal, Akarsh Sharma, Indu Bhat 		90
63 Improvement of cancer immunotherapy
Anna Carol Singh, Amit Kumar Chaurasia 		92
64 Pharmacogenomics for Personalized Medicine in the Indian Population: A Sustainable Healthcare Revolution
Aanya Tomer, Amit Kumar Chaurasia 		93
65 Cerium Oxide Nanomaterials as Therapeutic Agents
Vikash Lodhi, Sushant Singh 		94
66 Cross-talk between Brain Derived Neurotrophic Factor, Ferritin and Vitamin D Levels in Migraine: A Case-Control study
Radhika Bhadana, Maheen Mushtaq, Smita Jain 		96
67 Environmental and Health Implications of Textile Dyes: A Review with Emphasis on Microbial Bioremediation
Kajal Dan, Anamika Mehta 		98
68 Role of lncRNA In Acquired Therapy Resistance in Breast Cancer
Komal Barhela, Binayak Kumar 		100
69 Isolation and Screening of Laccase-producing Fungal Species
Deepali, Mohit Kumar, Santosh Kumar Mishra 		101
70 The Application of Cold Plasma for Improved Nutritional Quality in Desi Chickpea Seeds
Richa Gaur, Ranjana Pande 		102
71 The Limits of Brain Death Diagnosis: A Review of Neuroscientific Advances and Transplant Ethics
Reetu Yadav, Tripti, Ankur Kumar, Pragati Singh 		103
72 Role of GPR4 and LPAR4 Genes in Limb Development
Neha Singh, Chanu, Amitabh Bandyopadhyay 		105
73 Targeting Mitochondrial Proteins in Glioblastoma Using Phytocompounds from Elaeocarpus ganitrus
Mudra Sikenis, Subhabrata Kar 		107
74 Predictive Strength of Latent EBV Proteins for Prospective Oral Carcinoma
Prigya Sharma, Annette Angel, Vinod Joshi, Bennet Angel, Monika Dheer, Reshu Chauhan 		108
75 Microbial Powered Desalination System for Water Harvesting, Energy Production, and Wastewater Treatment
Rahul Kumar Mishra, Soumya Pandit 		110
76 Production of Feather Based Biocompost for Sustainable Agriculture
Musbahu Abdullahi Bagwai, Ranjeeta Bhari 		111
77 The Ubiquitin Proteasome System: A Regulator of Muscle Mass
Adeeba Khan, Deepakshi, Garima Gautama, Vikas Dutt 		112
78 Interplay Among the Centrins in Leishmania Donovani Parasites
Shital A. Selvapandiyan 		113
79 Science of Artificial Skin
Sneha Chauhan, Ashwini Kumar 		114
80 Interplay among the centrins in Leishmania donovani parasites.
Shital, A. Selvapandiyan
81 Structural and bio-physical characterization of zinc oxide nanoparticle of Aegle marmelos Leaf Extract
Maheen Mushtaq, Radhika Bhadana, Smita Jain
82 Hemocompatibility and Cytotoxicity Evaluation of Synthesized Thiosemicarbazones with Dual Antimicrobial Activity
Swati Bhati, Sonia Khanna, Soumi Sadhu
83 Genome-Based In-Silico Characterization of Coat Protein of Shallot Latent Virus Infecting Garlic Crops
Suvigya Drabu, Vineeta Yadav
84 Disrupting EMT Signalling Networks to Overcome Regorafenib Resistance
Anurag Mishra
85 Essential Oils as Natural Alternatives: Extraction methods and potential applications.
Ankita Aggarwal, Harsh Kumar Rawat